With rapid research advances in the genome of the Hevea brasiliensis rubber tree, more genomic and transcriptomic data have been generated. However, these data are still deposited in raw format in the National Centre for Biotechnology Information (NCBI) and other public databases, and therefore, data utilization is cumbersome for the scientists in the rubber research community. To overcome such issues, a comprehensive rubber tree data hub, HeveaDB, was constructed and maintained under the organization, the International Rubber Research and Development Board (IRRDB). The first version of the database, HeveaDB 1.0, contains four versions of H. brasiliensis draft genomes, 99 next-generation sequencing (NGS) transcriptomes, 21,619 annotated EST sequences, 12 curated gene families, 30,200 gene annotations, phenotype data of 5,049 wild Brazilian germplasm, and information on 19,141 rubber clones of Wickham origin. A selection of bioinformatic tools are integrated into the database to facilitate the utilization of the data by scientists who are not skilled in bioinformatics. With periodic updating and improvement of content and function, HeveaDB will serve as a useful platform for the molecular biological and genomic studies of the rubber tree.